Leukotriene-B

BT-AP08044

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human protein . at AA range: 400-480

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

This gene, CYP4F3, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. The enzyme starts the process of inactivating and degrading leukotriene B4, a potent mediator of inflammation. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F8, is approximately 18 kb away. Three transcript variants encoding two different isoforms have been found for this gene.

Human: Q08477; Mouse: Q99N16; Rat: Q3MID2;

Human: 4051

Leukotriene-B;4 omega-hydroxylase 2 ;EC 1.14.13.30;CYPIVF3;Cytochrome P450 4F3;Cytochrome P450-LTB-omega;Leukotriene-B;4 20-monooxygenase 2

Metabolism

CYP4F3