Full product name
Enhancer of mRNA-decapping protein 4
Code
BT-AP15368
Host
Rabbit
Isotype
IgG
Size
100ul,50ul,20ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from part region of human protein
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
In the process of mRNA degradation, seems to play a role in mRNA decapping. Component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. Promotes complex formation between DCP1A and DCP2. Enhances the Catalytic activity of DCP2 (in vitro).,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,Belongs to the WD repeat EDC4 family.,Contains 4 WD repeats.,subunit:Part of a decapping complex consisting of DCP1A, DCP2, EDC3, EDC4 and probably DDX6. Part of a complex consisting of DCP1A, EDC3, EDC4 and DDX6. Part of a complex consisting of DCP1B, EDC3, EDC4 and DDX6. Interacts with DCP2.,
Uniprot accession
Gene ID
Human: 23644
Synonyms
Enhancer of mRNA-decapping protein 4 ;Autoantigen Ge-1;Autoantigen RCD-8;Human enhancer of decapping large subunit;Hedls
Research area
Epigenetics and nuclear signaling
Target protein
EDC4