Ectonucleotide pyrophosphatase/phosphodiesterase family member 1

BT-AP08862

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from part region of human protein

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance.

Human: P22413; Mouse: P06802; Rat: Q924C3;

Human: 5167

Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 ;E-NPP 1;Membrane component chromosome 6 surface marker 1;Phosphodiesterase I/nucleotide pyrophosphatase 1;Plasma-cell membrane g

Cell biology; Metabolism; Signal transduction

ENPP1