Peptidyl-prolyl cis-trans isomerase FKBP4

BT-AP15604

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from part region of human protein

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. It interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes. This encoded protein is known to associate with phytanoyl-CoA alpha-hydroxylase. It can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors. This protein corr

Human: Q02790; Mouse: P30416; Rat: Q9QVC8;

Human: 2288

Peptidyl-prolyl cis-trans isomerase FKBP4 ;PPIase FKBP4;EC 5.2.1.8;51 kDa FK506-binding protein;FKBP51;52 kDa FK506-binding protein;52 kDa FKBP;FKBP-52;59 kDa immunophilin;p59;FK506-

Epigenetics and nuclear signaling; Signal transduction

FKBP4