Full product name
Glutamate receptor, ionotropic kainate 2
Code
BT-AP15781
Host
Rabbit
Isotype
IgG
Size
20ul,50ul,100ul
Clonality
Polyclonal
Immunogen
Synthetic Peptide of GRIK2 (GluR6)
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation.
Uniprot accession
Gene ID
Human: 2898
Synonyms
Glutamate receptor, ionotropic kainate 2 ;Excitatory amino acid receptor 4;EAA4;Glutamate receptor 6;GluR-6;GluR6; Glutamate receptor, ionotropic kainate 2; Excitatory amino acid receptor 4; EAA4; Glutamate receptor 6; GluR-6; GluR6
Research area
Neuroscience; Signal transduction
Target protein
GRIK2
