Haptoglobin

BT-AP09816

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthetic peptide from human protein at AA range: 300-360

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. The protein encoded also exhibits antimicrobial activity against bacteria. A similar duplicated gene is located nex

Human: P00738; Mouse: Q61646;

Human: 3240; Mouse: 15439

Haptoglobin ;Zonulin [Cleaved into: Haptoglobin alpha chain; Haptoglobin beta chain]; Haptoglobin; Zonulin; Haptoglobin alpha chain; Haptoglobin beta chain;

Cardiovascular; Cell biology; Signal transduction

HP