Histone deacetylase 8

BT-AP09852

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

The antiserum was produced against synthesized peptide derived from human HDAC8 around the phosphorylation site of Ser39. AA range:5-54

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.

Human: Q9BY41; Mouse: Q8VH37; Rat: B1WC68;

41758

Human: 55869; Mouse: 70315; Rat: 1.00912e+008

Histone deacetylase 8; HDAC8; HDACL1; CDA07; Histone deacetylase 8; HD8

Cardiovascular; Epigenetics and nuclear signaling; Stem cells

HDAC8