Full product name
Histone H2A.Z
Code
BT-AP09938
Host
Rabbit
Isotype
IgG
Size
20ul,50ul,100ul
Clonality
Polyclonal
Immunogen
Synthetic Peptide of Histone H2A.Z
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.
Formulation
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Storage
-20°C for 1 year
Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.
Uniprot accession
Molecular weight
51633
Gene ID
Human: 3015; Mouse: 51788; Rat: 58940
Synonyms
Histone H2A.Z; H2AFZ; H2AZ; Histone H2A.Z; H2A/z
Research area
Epigenetics and nuclear signaling
Target protein
H2AFZ
