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Home > Product > Antibody > hnRNP C1/2(Phospho Ser260) Polyclonal Antibody

hnRNP C1/2(Phospho Ser260) Polyclonal Antibody

hnRNP C1/2(Phospho Ser260) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, IHC-p, IF, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-p, IF, ELISA

Product overview

Full product name

Heterogeneous nuclear ribonucleoproteins C1/C2

Code

BT-AP10105

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human hnRNP C1/2 around the phosphorylation site of Ser260. AA range:231-280

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene.

Uniprot accession

Molecular weight

33670

Gene ID

Human: 3183; Mouse: 15381

Synonyms

Heterogeneous nuclear ribonucleoproteins C1/C2; HNRNPC; HNRPC; Heterogeneous nuclear ribonucleoproteins C1/C2; hnRNP C1/C2

Research area

Epigenetics and nuclear signaling

Target protein

HNRNPC

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
IHC-p 1: 100 - 1: 300
ELISA 1: 20000

Images

Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100(4°C overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
Immunohistochemistry analysis of paraffin-embedded human brain, using hnRNP C1/2 (Phospho-Ser260) Antibody. The picture on the right is blocked with the phospho peptide.
Western Blot analysis of 293 cells using Phospho-hnRNP C1/2 (S260) Polyclonal Antibody
Western blot analysis of lysates from 293 cells treated with H2O2 100uM 15', using hnRNP C1/2 (Phospho-Ser260) Antibody. The lane on the right is blocked with the phospho peptide.

Protocols

References

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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