Homeobox protein Hox-B8

BT-AP10241

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from part region of human protein

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.

Human: P17481; Mouse: P09632; Rat: P18863;

Human: 3218

Homeobox protein Hox-B8 ;Homeobox protein Hox-2.4;Homeobox protein Hox-2D

Cancer; Developmental biology; Epigenetics and nuclear signaling; Stem cells

HOXB8