JAK2(Phospho Tyr570) Polyclonal Antibody

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Blood coagulation
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Signal transduction
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Home > Product > Antibody > JAK2(Phospho Tyr570) Polyclonal Antibody

JAK2(Phospho Tyr570) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, IHC-p, IF, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-p, IF, ELISA

Product overview

Full product name

Tyrosine-protein kinase JAK2

Code

BT-AP10560

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human JAK2 around the phosphorylation site of Tyr570. AA range:541-590

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

Uniprot accession

Human: O60674; Mouse: Q62120; Rat: Q62689;

Molecular weight

130674

Gene ID

Human: 3717; Mouse: 16452; Rat: 24514

Synonyms

Tyrosine-protein kinase JAK2; JAK2; Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2

Research area

Cancer; Cell biology; Epigenetics and nuclear signaling; Signal transduction; Microbiology

Target protein

JAK2

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
IHC-p	1: 100 - 1: 300
ELISA	1: 5000

Images

Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100(4°C overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.

Western Blot analysis of 293 cells using Phospho-JAK2 (Y570) Polyclonal Antibody

Western blot analysis of lysates from 293 cells treated with etoposide 25uM 24h, using JAK2 (Phospho-Tyr570) Antibody. The lane on the right is blocked with the phospho peptide.

Protocols

> Protocol Booklet

References

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

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Lead time: Within one week

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