Histone acetyltransferase KAT6B

BT-AP10619

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human protein . at AA range: 1170-1250

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene.

Human: Q8WYB5; Mouse: Q8BRB7;

Human: 23522

Histone acetyltransferase KAT6B ;EC 2.3.1.48;Histone acetyltransferase MOZ2;MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4;MYST-4;Monocytic leukemia zinc finger protein-related factor

Epigenetics and nuclear signaling

KAT6B