Full product name
Histone acetyltransferase KAT6B
Code
BT-AP10619
Host
Rabbit
Isotype
IgG
Size
100ul,50ul,20ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human protein . at AA range: 1170-1250
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene.
Uniprot accession
Gene ID
Human: 23522
Synonyms
Histone acetyltransferase KAT6B ;EC 2.3.1.48;Histone acetyltransferase MOZ2;MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4;MYST-4;Monocytic leukemia zinc finger protein-related factor
Research area
Epigenetics and nuclear signaling
Target protein
KAT6B
