LKB1(Phospho Ser428) Polyclonal Antibody

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Home > Product > Antibody > LKB1(Phospho Ser428) Polyclonal Antibody

LKB1(Phospho Ser428) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Cow

Applications: WB, IHC-p, IF, ICC, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Cow

Applications: WB, IHC-p, IF, ICC, ELISA

Product overview

Full product name

Serine/threonine-protein kinase STK11

Code

BT-AP10933

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human LKB1 around the phosphorylation site of Ser428. AA range:384-433

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for 1 year

Background

This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Uniprot accession

Human: Q15831; Mouse: Q9WTK7;

Molecular weight

48636

Gene ID

Human: 6794; Mouse: 20869

Synonyms

Serine/threonine-protein kinase STK11; STK11; LKB1; PJS; Serine/threonine-protein kinase STK11; Liver kinase B1; LKB1; hLKB1; Renal carcinoma antigen NY-REN-19

Research area

Cancer; Cell biology; Metabolism

Target protein

STK11

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
IHC-p	1: 100 - 1: 300
IF	1: 200 - 1: 1000
ICC	1: 200 - 1: 1000
ELISA	1: 40000

Images

Immunofluorescence analysis of Hela cell. LKB1 (phospho Ser428) Polyclonal Antibody(Red) was diluted at 1:200(4°C overnight). NSE Monoclonal Antibody(13E2)(Green) was diluted at 1:200(4°C overnight).

Immunofluorescence analysis of NIH/3T3 cells, using LKB1 (Phospho-Ser428) Antibody. The picture on the right is blocked with the phospho peptide.

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using LKB1 (Phospho-Ser428) Antibody. The picture on the right is blocked with the phospho peptide.

Western blot analysis of lysates from HeLa cells treated with PMA 125ng/ml 30', using LKB1 (Phospho-Ser428) Antibody. The lane on the right is blocked with the phospho peptide.

Protocols

> Protocol Booklet

References

Customer reviews and Q&As

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

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