Mitogen-activated protein kinase kinase kinase kinase 2

BT-AP11029

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human protein . at AA range: 400-480

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. Alternative splicing results in multiple transcript variants.

Human: Q12851; Mouse: Q61161;

Human: 5871

Mitogen-activated protein kinase kinase kinase kinase 2 ;EC 2.7.11.1;B lymphocyte serine/threonine-protein kinase;Germinal center kinase;GC kinase;MAPK/ERK kinase kinase kinase 2;MEK kinase

Signal transduction

MAP4K2