Mitogen-activated protein kinase kinase kinase 11

BT-AP11376

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized phospho-peptide around the phosphorylation site of human MLK3 (phospho Ser674)

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.

Human: Q16584; Mouse: Q80XI6; Rat: Q66HA1;

92688

Human: 4296; Mouse: 26403; Rat: 309168

Mitogen-activated protein kinase kinase kinase 11; MAP3K11; MLK3; PTK1; SPRK; Mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Src-homology 3 domain-containing proline-rich kinase

Signal transduction

MAP3K11