Full product name
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial
Code
BT-AP11783
Host
Rabbit
Isotype
IgG
Size
20ul,50ul,100ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human protein . at AA range: 90-170
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
This gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome.
Uniprot accession
Gene ID
Human: 4728
Synonyms
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial ;EC 1.6.5.3;EC 1.6.99.3;Complex I-23kD;CI-23kD;NADH-ubiquinone oxidoreductase 23 kDa subunit;TYKY subunit
Research area
Cancer; Metabolism; Signal transduction; Tags & cell markers
Target protein
NDUFS8