Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

BT-AP12186

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from human protein . at AA range: 160-240

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene.

Human: P11177; Mouse: Q9D051; Rat: P49432;

Human: 5162

Pyruvate dehydrogenase E1 component subunit beta, mitochondrial ;PDHE1-B;EC 1.2.4.1

Cancer; Metabolism; Signal transduction; Tags & cell markers

PDHB