Ribosomal protein S6 kinase beta-1

BT-AP12697

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized phospho-peptide around the phosphorylation site of human p70 S6 kinase α (phospho Thr421)

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.

Human: P23443; Mouse: Q8BSK8; Rat: P67999;

59140

Human: 6198; Mouse: 72508; Rat: 83840

Ribosomal protein S6 kinase beta-1; RPS6KB1; STK14A; Ribosomal protein S6 kinase beta-1; S6K-beta-1; S6K1; 70 kDa ribosomal protein S6 kinase 1; P70S6K1; p70-S6K 1; Ribosomal protein S6 kinase I; Serine/threonine-protein kinase 14A; p70 ribosomal S6 kinase alpha; p70 S6 kinas

Cell biology; Epigenetics and nuclear signaling; Metabolism; Signal transduction

RPS6KB1