Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B

BT-AP12869

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from part region of human protein

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Human: Q01064; Mouse: Q01065; Rat: Q01066;

Human: 5153

Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B ;Cam-PDE 1B;EC 3.1.4.17;63 kDa Cam-PDE

Signal transduction

PDE1B