cGMP-inhibited 3',5'-cyclic phosphodiesterase A

BT-AP12871

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human protein . at AA range: 250-330

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Human: Q14432; Mouse: Q9Z0X4; Rat: Q62865;

Human: 5139

cGMP-inhibited 3',5'-cyclic phosphodiesterase A ;EC 3.1.4.17;Cyclic GMP-inhibited phosphodiesterase A;CGI-PDE A

Signal transduction

PDE3A