cGMP-specific 3',5'-cyclic phosphodiesterase

BT-AP12876

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from part region of human protein

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.

Human: O76074; Mouse: Q8CG03; Rat: O54735;

Human: 8654

cGMP-specific 3',5'-cyclic phosphodiesterase ;EC 3.1.4.35;cGMP-binding cGMP-specific phosphodiesterase;CGB-PDE

Cancer; Cardiovascular; Cell biology; Metabolism; Signal transduction

PDE5A