Full product name
Platelet-derived growth factor receptor alpha
Code
BT-AP12881
Host
Rabbit
Isotype
IgG
Size
20ul,50ul,100ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human PDGFR α Polyclonal
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
Uniprot accession
Gene ID
Human: 5156; Mouse: 18595; Rat: 25267
Synonyms
Platelet-derived growth factor receptor alpha ;PDGF-R-alpha;PDGFR-alpha;EC 2.7.10.1;Alpha platelet-derived growth factor receptor;Alpha-type platelet-derived growth factor receptor;CD140 ant; Platelet-derived growth factor receptor alpha; PDGF-R-alpha; PDGFR-alpha; EC 2.7.10.1; Alpha platelet-derived growth factor receptor; Alpha-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD140a antigen; Platelet-derived growth factor alpha receptor; Platelet-derived growth factor receptor 2; PDGFR-2; CD antigen CD140a
Research area
Cancer; Cardiovascular; Signal transduction; Stem cells
Target protein
PDGFRA
