[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

BT-AP12908

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human protein . at AA range: 180-260

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex. Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits. Two catalytic subunits have been reported; one is predominantly expressed in skeletal muscle and another one is is much more abundant in the liver. The catalytic subunit, encoded by this gene, is the former, and belongs to the protein phosphatase 2C (PP2C) superfamily. Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases, this enzy

Human: Q9P0J1; Mouse: Q3UV70; Rat: O88483;

Human: 54704

[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial ;PDP 1;EC 3.1.3.43;Protein phosphatase 2C;Pyruvate dehydrogenase phosphatase catalytic subunit 1;PDPC 1

Cancer; Metabolism; Signal transduction; Tags & cell markers

PDP1