Serine/threonine-protein kinase N3

BT-AP13131

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from part region of human protein

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,The C1 domain does not bind the diacylglycerol (DAG).,enzyme regulation:Two specific sites, Thr-718 (activation loop of the kinase domain) and Thr-860 (turn motif), need to be phosphorylated for its full activation.,Contributes to invasiveness in malignant prostate cancer.,PTM:Autophosphorylated.,Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.,Contains 1 AGC-kinase C-terminal domain.,Contains 1 protein kinase domain.,Contains 3 REM (Hr1) repeats.,subcellular location:Nuclear and perinuclear Golgi region.,tissue specificity:Expressed in prostate tumors and various cancer cell lines. Not expressed in adult tissues.,

Human: Q6P5Z2; Mouse: Q8K045;

Human: 29941

Serine/threonine-protein kinase N3 ;EC 2.7.11.13;Protein kinase PKN-beta;Protein-kinase C-related kinase 3

Signal transduction

PKN3