Serum paraoxonase/arylesterase 2

BT-AP13227

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from part region of human protein

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.

Human: Q15165; Mouse: Q62086; Rat: Q6AXM8;

Human: 5445

Serum paraoxonase/arylesterase 2 ;PON 2;EC 3.1.1.2;EC 3.1.1.81;Aromatic esterase 2;A-esterase 2;Serum aryldialkylphosphatase 2

Cardiovascular; Metabolism; Neuroscience; Signal transduction

PON2