Full product name
Rab11 family-interacting protein 5
Code
BT-AP13683
Host
Rabbit
Isotype
IgG
Size
100ul,50ul,20ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human protein . at AA range: 570-650
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
disease:Antibodies against RIP11 are found in sera from patients with systemic lupus erythematosus (SLE) or Sjoegren syndrome (SS), and in the sera from mothers of children with neonatal lupus erythematosus (NLE).,Binds to vesicles enriched in neutral phospholipids via its C2 domain. The interaction is favored by Mg(2+) rather than Ca(2+).,Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma membrane.,PTM:Phosphorylated on serine and threonine residues.,Contains 1 C2 domain.,subunit:Forms an heterooligomeric complex with RAB11FIP4. Binds NAPG and SSA2. Binds RAB11A that has been activated by GTP binding.,tissue specificity:Detected at low levels in heart, brain, placenta, lung, liver, adipocytes, kidney, spleen, skeletal muscle and pancreas.,
Uniprot accession
Gene ID
Human: 26056
Synonyms
Rab11 family-interacting protein 5 ;Rab11-FIP5;Gamma-SNAP-associated factor 1;Gaf-1;Phosphoprotein pp75;Rab11-interacting protein Rip11
Research area
Metabolism; Signal transduction; Tags & cell markers
Target protein
RAB11FIP5
