E3 ubiquitin-protein ligase TRIM21

BT-AP13871

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from human protein . at AA range: 140-220

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.

Human: P19474; Mouse: Q62191;

Human: 6737

E3 ubiquitin-protein ligase TRIM21 ;EC 6.3.2.-;52 kDa Ro protein;52 kDa ribonucleoprotein autoantigen Ro/SS-A;RING finger protein 81;Ro;SS-A;Sjoegren syndrome type A antigen;SS-A;Tripar

Epigenetics and nuclear signaling; Immunology

TRIM21