Sodium channel protein type 11 subunit alpha

BT-AP14080

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from part region of human protein

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers.

Human: Q9UI33; Mouse: Q9R053; Rat: O88457;

Human: 11280

Sodium channel protein type 11 subunit alpha ;Peripheral nerve sodium channel 5;PN5;Sensory neuron sodium channel 2;Sodium channel protein type XI subunit alpha;Voltage-gated sodium channel su

Neuroscience

SCN11A