SH2B adapter protein 3

BT-AP14183

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from part region of human protein

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Human: Q9UQQ2; Mouse: O09039; Rat: P50745;

Human: 10019

SH2B adapter protein 3 ;Lymphocyte adapter protein;Lymphocyte-specific adapter protein Lnk;Signal transduction protein Lnk

Immunology; Signal transduction

SH2B3