Full product name
Serine/threonine-protein kinase SIK2
Code
BT-AP14228
Host
Rabbit
Isotype
IgG
Size
100ul,50ul,20ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from part region of human protein
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-175 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.,Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily.,Contains 1 protein kinase domain.,Contains 1 UBA domain.,subunit:Interacts with and phosphorylates TORC2/CRTC2.,
Uniprot accession
Gene ID
Human: 23235
Synonyms
Serine/threonine-protein kinase SIK2 ;EC 2.7.11.1;Qin-induced kinase;Salt-inducible kinase 2;SIK-2;Serine/threonine-protein kinase SNF1-like kinase 2
Research area
Cardiovascular; Signal transduction
Target protein
SIK2
