Superoxide dismutase [Cu-Zn]

BT-AP14363

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from the Internal region of human SOD-1.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

-20°C for 1 year

The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

Human: P00441; Mouse: P08228; Rat: P07632;

Human: 6647

Superoxide dismutase [Cu-Zn]; SOD1; Superoxide dismutase [Cu-Zn; ; Superoxide dismutase 1; hSod1

Signal transduction; Cell biology; Metabolism; Cancer

SOD1