SAM pointed domain-containing Ets transcription factor

BT-AP14414

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from human protein . at AA range: 140-220

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Human: O95238; Mouse: Q9WTP3;

Human: 25803

SAM pointed domain-containing Ets transcription factor ;Prostate epithelium-specific Ets transcription factor;Prostate-specific Ets;Prostate-derived Ets factor

Epigenetics and nuclear signaling; Cancer

SPDEF