Nucleolysin TIA-1 isoform p40

BT-AP14949

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from human protein . at AA range: 201-250

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.

Human: P31483; Mouse: P52912;

Human: 7072

Nucleolysin TIA-1 isoform p40 ;RNA-binding protein TIA-1;T-cell-restricted intracellular antigen-1;TIA-1;p40-TIA-1

Epigenetics and nuclear signaling; Cancer; Cell biology; Immunology

TIA1