T-lymphoma invasion and metastasis-inducing protein 1

BT-AP14951

Rabbit

IgG

100ul,50ul,20ul

Polyclonal

Synthesized peptide derived from part region of human protein

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA.,Belongs to the TIAM family.,Contains 1 DH (DBL-homology) domain.,Contains 1 PDZ (DHR) domain.,Contains 1 PH domain.,Contains 1 RBD (Ras-binding) domain.,Contains 2 PH domains.,subunit:Interacts with BAIAP2.,tissue specificity:Found in virtually all analyzed tumor cell lines including B- and T-lymphomas, neuroblastomas, melanomas and carcinomas.,

Human: Q13009; Mouse: Q60610;

Human: 7074

T-lymphoma invasion and metastasis-inducing protein 1 ;TIAM-1

Signal transduction

TIAM1