Toll-like receptor 6

BT-AP15007

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Recombinant Protein of TLR6

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

-20°C for 1 year

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins. A Ser249Pro polymorphism in the extracellular domain of the encoded protein may be associated with an increased of asthma is some populations.

Human: Q9Y2C9; Mouse: Q9EPW9;

Human: 10333

Toll-like receptor 6; Toll-like receptor 6; CD286

Immunology; Microbiology; Epigenetics and nuclear signaling; Cardiovascular; Signal transduction

TLR6