Ubiquitin-conjugating enzyme E2 D3

BT-AP15278

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from part region of human protein

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

-20°C for 1 year

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.

Human: P61077; Mouse: P61079; Rat: P61078;

Human: 7323

Ubiquitin-conjugating enzyme E2 D3 ;EC 6.3.2.19;Ubiquitin carrier protein D3;Ubiquitin-conjugating enzyme E2;17KB 3;Ubiquitin-conjugating enzyme E2-17 kDa 3;Ubiquitin-protein ligase D3

Epigenetics and nuclear signaling; Cell biology

UBE2D3