Full product name
Ubiquitin carboxyl-terminal hydrolase 6
Code
BT-AP15330
Host
Rabbit
Isotype
IgG
Size
100ul,50ul,20ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from part region of human protein
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Storage
-20°C for 1 year
Background
Catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,disease:Involved in tumorigenesis.,Has an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity.,miscellaneous:The USP6 gene only exists in the primate lineage.,Belongs to the peptidase C19 family.,Contains 1 Rab-GAP TBC domain.,tissue specificity:Testis specific. Expressed in various cancer cell lines.,
Uniprot accession
Gene ID
Human: 9098
Synonyms
Ubiquitin carboxyl-terminal hydrolase 6 ;EC 3.4.19.12;Deubiquitinating enzyme 6;Proto-oncogene TRE-2;Ubiquitin thioesterase 6;Ubiquitin-specific-processing protease 6
Research area
Cell biology; Epigenetics and nuclear signaling
Target protein
USP6
