Guanine nucleotide exchange factor VAV3

BT-AP15438

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized phospho-peptide around the phosphorylation site of human Vav3 (phospho Tyr173)

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Human: Q9UKW4; Mouse: Q9R0C8;

97776

Human: 10451; Mouse: 57257

Guanine nucleotide exchange factor VAV3; VAV3; Guanine nucleotide exchange factor VAV3; VAV-3

Signal transduction; Cancer

VAV3