Tumor necrosis factor ligand superfamily member 15

BT-AP15461

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from Tumor necrosis factor ligand superfamily member 15 at AA range: 51-100

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for 1 year

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene.

Human: O95150; Mouse: Q5UBV8; Rat: Q8K3Y7;

28087

Human: 9966; Mouse: 326623; Rat: 252878

Tumor necrosis factor ligand superfamily member 15; TNFSF15; TL1; VEGI; Tumor necrosis factor ligand superfamily member 15; TNF ligand-related molecule 1; Vascular endothelial cell growth inhibitor

Epigenetics and nuclear signaling; Cardiovascular; Immunology

TNFSF15