Code
BT-MCA2787
Host
Mouse
Isotype
Mouse IgG2a
Size
100μL,50μL
Clonality
Monoclonal
Immunogen
Purified recombinant fragment of Dynamin-2 expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
Dynamin-2 (Dyn2), with 870-amino acid protein (about 95kDa), belongs to the dynamin family. Dynamin-1 (neuron-specific), dynamin-2 (ubiquitously expressed), and dynamin-3 (expressed only in the testis, brain, and lung), constitute the dynamin family. Members of the dynamin family are GPTase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin 1 is expressed exclusively in neurons, Dynamin 2 is ubiquitously expressed and Dynamin 3 is thought to be restricted to expression in the brain, testis, heart, and lung. The dynamins participate in the cellular process of clathrin-mediated and fluid-phase endocytosis.
Uniprot accession
Gene ID
1785
Synonyms
DYN2;DYNII;CMTDI1;CMTDIB;DI-CMTB;DNM2
Research area
Others
Target protein
Dynamin-2
