Code
BT-MCA2154
Host
Mouse
Isotype
Mouse IgG1
Size
100μL,50μL
Clonality
Monoclonal
Immunogen
Purified recombinant fragment of human CD334 (AA: extra 22-369) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term.
Background
The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways, including cell proliferation, cell differentiation, cell migration, lipid metabolism, bile acid biosynthesis, vitamin D metabolism, glucose uptake, and phosphate homeostasis. This protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. [provided by RefSeq, Aug 2017]
Uniprot accession
Molecular weight
88kDa
Gene ID
2264
Synonyms
FGFR4;TKF;JTK2
Research area
Others
Target protein
CD334
