14-3-3 epsilon Antibody

BT-AP00006

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

The antiserum was produced against synthesized peptide derived from human 14-3-3 epsilon. AA range:206-255

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for YWHAE.

Human: P62258; Mouse: P62259; Rat: P62260;

29174

Human: 7531; Mouse: 22627; Rat: 29753

YWHAE; 14-3-3 protein epsilon; 14-3-3E

Neuroscience; Signal Transduction

YWHAE