Actin-alpha cardiac muscle Antibody

BT-AP00219

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from Actin-α cardiac muscle . at AA range: 1-80

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. Actin alpha cardiac muscle 1 encoded by ACTC1 belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).

Human: P68032; Mouse: P68033; Rat: P68035;

42019

Human: 70; Mouse: 11464; Rat: 29275

ACTC1; ACTC; Actin, alpha cardiac muscle 1; Alpha-cardiac actin

Signal Transduction; Cardiovascular

ACTC1