Axl Antibody

BT-AP00783

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from Axl . at AA range: 630-710

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

The protein encoded by AXL (AXL receptor tyrosine kinase) is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). AXL may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of AXL.

Human: P30530; Mouse: Q00993;

97437

Human: 558; Mouse: 26362

AXL; UFO; Tyrosine-protein kinase receptor UFO; AXL oncogene

Cell Biology

AXL