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Home > Product > Antibody > CLC-7 Polyclonal Antibody

CLC-7 Polyclonal Antibody

CLC-7 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ELISA

Product overview

Full product name

CLC-7 Antibody

Code

BT-AP01864

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human CLCN7. AA range:10-59

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

The product of CLCN7 belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. CLCN7 encodes chloride channel 7. Defects in CLCN7 are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood.

Uniprot accession

Molecular weight

88679

Gene ID

Human: 1186; Mouse: 26373; Rat: 29233

Synonyms

CLCN7; H(+)/Cl(-) exchange transporter 7; Chloride channel 7 alpha subunit; Chloride channel protein 7; ClC-7

Research area

Signal Transduction; Metabolism

Target protein

CLCN7

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
ELISA 1: 40000

Images

Western blot analysis of CLCN7 Antibody. The lane on the right is blocked with the CLCN7 peptide.
Western Blot analysis of A549 cells using CLC-7 Polyclonal Antibody diluted at 1:500
Western blot analysis of the lysates from COLO205 cells using CLCN7 antibody.

Protocols

References

Customer reviews and Q&As

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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