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Home > Product > Antibody > Cleaved-Integrin Alpha5 HC (F42) Polyclonal Antibody

Cleaved-Integrin Alpha5 HC (F42) Polyclonal Antibody

Cleaved-Integrin Alpha5 HC (F42) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse

Applications: WB, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, ELISA

Product overview

Full product name

Cleaved-Integrin alpha5 HC (F42) Antibody

Code

BT-AP01929

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human ITGA5. AA range:23-72

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

The product of ITGA5 belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

Uniprot accession

Molecular weight

114536

Gene ID

Human: 3678; Mouse: 16402

Synonyms

ITGA5; FNRA; Integrin alpha-5; CD49 antigen-like family member E; Fibronectin receptor subunit alpha; Integrin alpha-F; VLA-5; CD antigen CD49e

Research area

Signal Transduction

Target protein

ITGA5

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
ELISA 1: 10000

Images

Western blot analysis of lysates from NIH/3T3 cells, treated with etoposide 25uM 24h, using ITGA5 (heavy chain,Cleaved-Phe42) Antibody. The lane on the right is blocked with the synthesized peptide.

Protocols

References

Customer reviews and Q&As

No reviews
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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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