CYP1B1 Antibody

BT-AP02382

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from the Internal region of human CYP1B1.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

CYP1B1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in CYP1B1 have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.

Human: Q16678; Mouse: Q64429;

60846

Human: 1545

CYP1B1; Cytochrome P450 1B1; CYPIB1

Cardiovascular

CYP1B1