D4DR Antibody

BT-AP02487

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

The antiserum was produced against synthesized peptide derived from human DRD4. AA range:355-404

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

DRD4 encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in DRD4 have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. DRD4 contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.

Human: P21917; Mouse: P51436; Rat: P30729;

48361

Human: 1815; Mouse: 13491; Rat: 25432

DRD4; D(4) dopamine receptor; D(2C) dopamine receptor; Dopamine D4 receptor

Neuroscience

DRD4