FAM80A Antibody

BT-AP03154

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

The antiserum was produced against synthesized peptide derived from human RIMKA. AA range:112-161

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

RIMKLA (N-acetylaspartyl-glutamate synthetase A) is a 391 amino acid protein that belongs to the rimK family. Localizing to cytoplasm, RIMKLA contains one ATP-grasp domain and binds two manganese ions per subunit. RIMKLA catalyzes the synthesis of N-acetylaspartyl-glutamate (NAAG). RIMKLA, is almost exclusively expressed in the CNS, whereas RIMKLB, which shares 65% sequence identity with RIMKLA, is expressed in CNS and testis. It has also been suggested that RIMKLA and RIMKLB also served to ligate free glutamate to (an) acceptor (s). RIMKLA catalyzed the ATP-dependent synthesis of N-acetylaspartylglutamate (NAAG) from N-acetylaspartate and L-glutamate. RIMKLB catalyzed this reaction as well as the synthesis of β-citrylglutamate. The RIMKLA gene is conserved in chimpanzee, dog, cow and mouse, and maps to human chromosome 1p34.2.

Human: Q8IXN7; Mouse: Q6PFX8;

42864

Human: 284716; Mouse: 194237

RIMKLA; FAM80A; N-acetylaspartyl-glutamate synthetase A; NAAG synthetase A; NAAGS; Ribosomal protein S6 modification-like protein A

Others

RIMKLA